Post by Dave on Sept 12, 2021 15:12:36 GMT -5
Robert – you have no idea of what you speak!
R" First Dave, the assujmptions when using the Standard Deviation test.
I used to have a calculator for doing such sums, SD = Sum (x2 - mean)/number of trials
So what can we determine from this? The smaller the standard deviation, the less risky an investment will be, dollar-for-dollar. On the other hand, the larger the variance and standard deviation, the more volatile a security.
SD – is an indicator od precision and systemic error (things I can control)
CV – is a measure of random error (things I cannot control)
D"What about 3,3,3,3,3, my mean = 3 my SD = 0
R" If there is no variance, the SD does not measure anything.
SD is an indicator precision – on the rifle range 3,3,3,3,3 is a perfectly tight group – just not accurate
Before I shoot in a contest – or measure a patient – I run QC
I hang a target – I sample a KNOWN (a known measured value – a standard)
A perfect score on 5 shoots = 50 – my test sample measures 15 (3,3,3,3,3)
Calibration – is required – the shooter will adjust his sights – a lab guy plays maintaining or math games with his instrument to bring that precision accurately to the bulls eye
SD – is an indicator of precision and systemic error (things I can control)
Shooting – my gun – my sights – the calibration of my sights – my breathing
Medicine – my instrument – calibration – the way I Handel samples
CV – is a measure of random error (things I cannot control)
Shooting – the manufacture of the ammo – the wind – the humidity – atm pressure
Medicine – (pre-analytical error – quality of sample) – the electric grid that day – the temp – the altitude
Question: Should you get variance from a PCR test, if the primer is targeting specified RNA information?
I get what you are saying, the test process has flaws and so makes variance during the testing process.
Is this a valid testing process than? To say a person is 95% confident that they are negative or positive for COV19?
1- the goal is 2SD – the goal is 98% - 95% is just realistic
2- value – better than reading tea leaves or chicken entrails – or guessing
This requires the test is repeated say 10 times for each swab that is collected? DO they do this testing?
Or is the testing done only once per swab?
Rapid test is a one shot deal – it destroys the swab
How do you calibrate a PCR test - 98% of positive testing swabs must also grow the viron in a growth medium
D"Where are the human rights in a war between men?
R" I thought the world have rules for things used in war? So all bets are off are they?
So it's OK to torture a USA prisoner of war, like that Australian a few years back?
Just jump to extremes – it is what you do to prove you are serious
Beat your wife until she loves you more as well
R" First Dave, the assujmptions when using the Standard Deviation test.
I used to have a calculator for doing such sums, SD = Sum (x2 - mean)/number of trials
So what can we determine from this? The smaller the standard deviation, the less risky an investment will be, dollar-for-dollar. On the other hand, the larger the variance and standard deviation, the more volatile a security.
SD – is an indicator od precision and systemic error (things I can control)
CV – is a measure of random error (things I cannot control)
D"What about 3,3,3,3,3, my mean = 3 my SD = 0
R" If there is no variance, the SD does not measure anything.
SD is an indicator precision – on the rifle range 3,3,3,3,3 is a perfectly tight group – just not accurate
Before I shoot in a contest – or measure a patient – I run QC
I hang a target – I sample a KNOWN (a known measured value – a standard)
A perfect score on 5 shoots = 50 – my test sample measures 15 (3,3,3,3,3)
Calibration – is required – the shooter will adjust his sights – a lab guy plays maintaining or math games with his instrument to bring that precision accurately to the bulls eye
SD – is an indicator of precision and systemic error (things I can control)
Shooting – my gun – my sights – the calibration of my sights – my breathing
Medicine – my instrument – calibration – the way I Handel samples
CV – is a measure of random error (things I cannot control)
Shooting – the manufacture of the ammo – the wind – the humidity – atm pressure
Medicine – (pre-analytical error – quality of sample) – the electric grid that day – the temp – the altitude
Question: Should you get variance from a PCR test, if the primer is targeting specified RNA information?
I get what you are saying, the test process has flaws and so makes variance during the testing process.
Is this a valid testing process than? To say a person is 95% confident that they are negative or positive for COV19?
1- the goal is 2SD – the goal is 98% - 95% is just realistic
2- value – better than reading tea leaves or chicken entrails – or guessing
This requires the test is repeated say 10 times for each swab that is collected? DO they do this testing?
Or is the testing done only once per swab?
Rapid test is a one shot deal – it destroys the swab
How do you calibrate a PCR test - 98% of positive testing swabs must also grow the viron in a growth medium
D"Where are the human rights in a war between men?
R" I thought the world have rules for things used in war? So all bets are off are they?
So it's OK to torture a USA prisoner of war, like that Australian a few years back?
Just jump to extremes – it is what you do to prove you are serious
Beat your wife until she loves you more as well